De novo asymmetric syntheses of d-, l- and 8-epi-d-swainsonine
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چکیده
منابع مشابه
De novo synthesis of D- and L-fucosamine containing disaccharides
The availability of rare monosaccharides that cannot be isolated from natural sources is currently limiting the access to the synthesis and the biological evaluation of complex bacterial cell-surface glycans. Here, we report the synthesis of D- and L-fucosamine building blocks by a de novo approach from L- and D-Garner aldehydes. These differentially protected monosaccharide building blocks wer...
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The total syntheses of basiliolide C and previously unreported epi-basiliolide C are achieved by an Ireland-Claisen/Diels-Alder cascade. The development of a palladium catalyzed cross-coupling of methoxy alkynyl zinc reagents allows for the protecting-group-free syntheses of transtaganolides C and D. Syntheses of transtaganolides C and D are accomplished in a single operation to generate three ...
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Abstracfi This paper describes preparations of o(and r--) chlorolactic acids having enantiomeric excesses greater than 977o by o(and l-) lactate dehydrogenase catalyzed reduction of chloropyruvic acid with NADH. In syntheses carried out on 0.1{).5-mol scales, the NADH was regenerated in situ by using glucose 6-phosphate and glucose 6-phosphate dehydrogenase. The enantiomerically enriched chloro...
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ژورنال
عنوان ژورنال: Tetrahedron
سال: 2008
ISSN: 0040-4020
DOI: 10.1016/j.tet.2007.10.109